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M94A3022.TXT
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1994-10-25
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Document 3022
DOCN M94A3022
TI Improvement in diagnosis of visceral Kaposi-sarcoma by endoscopic
ultrasound (EUS).
DT 9412
AU Goebel FD; Bogner JR; Liess H; Zoller WG; Medizinische Poliklinik,
University of Munich, Germany.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):171 (abstract no. PB0111). Unique
Identifier : AIDSLINE ICA10/94369553
AB OBJECTIVE: Almost 50% of the patients with AIDS and Kaposi Sarcoma (KS)
as the most frequently occurring tumor show visceral involvement.
Gastrointestinal KS usually is diagnosed using endoscopy. To evaluate
the use of Endoscopic Ultrasound as a complementary method scans were
performed to assess informations about distribution pattern and
anatomical relation to mucosa, submucosa and muscularis propria.
METHODS/PATIENTS: 22 homosexual pts. (aged 41 +/- 9 years) were enrolled
prospectively during a 12-months recruitment period. Endoscopy and EUS
was performed in each patient. RESULTS: Physical examination and
inspection of the oral cavity revealed mucocutaneous KS in 21 pts.,
including 10 pts. with palatinal KS. Endoscopy showed lesions in 13
pts., usually of nodular character. One patient who produced GI-symptoms
showed KS in the stomach exclusively. Additional EUS detected 60 lesions
suggestive of KS in 19 pts.: n = 9 esophagus, n = 10 cardia, n = 9
fundus, n = 10 corpus, n = 8 antrum, n = 8 bulbus duodeni and n = 6 pars
desc. duodeni. 63% of the lesions seen by EUS (38/60) presented with
involvement of mucosa and submucosa while 16.7% (10/60) showed lesions
throughout all three layers. 20% of the lesions (12/60) solely involved
submucosa and muscularis propria. These lesions were not visible in
endoscopy. Sonomorphologically they showed a similar pattern to those
seen in endoscopy and EUS. CONCLUSIONS: These results support the
hypothesis, that EUS provides information on KS involvement of different
tissue layers in the GI-tract. A higher number of lesions is detected by
EUS as compared to endoscopy. This is due to visualization of tumors
which do not involve the mucosa and therefore evade endoscopic
diagnosis.
DE Acquired Immunodeficiency Syndrome/*ULTRASONOGRAPHY Adult *Endoscopy,
Gastrointestinal Gastrointestinal Neoplasms/*ULTRASONOGRAPHY
Homosexuality Human Male Middle Age Prospective Studies Sarcoma,
Kaposi's/*ULTRASONOGRAPHY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).